epitope-specific

epitope-specific
эпитоп-специфический

English-Russian small dictionary of medicine. . 2015.

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  • epitope tag — Short peptide sequence that constitutes an epitope for an existing antibody. Widely used in molecular biology to ‘tag’ transgenic proteins (as a translational fusion product) to follow their expression and fate by immunocytochemistry or Western… …   Dictionary of molecular biology

  • epitope — noun Etymology: International Scientific Vocabulary, from epi + Greek topos place Date: 1960 a molecular region on the surface of an antigen capable of eliciting an immune response and of combining with the specific antibody produced by such a… …   New Collegiate Dictionary

  • epitope — (ep i tōp) An area of the antigen molecule that stimulates the production of, and combines with, specific antibodies; also known as the antigenic determinant site …   Dictionary of microbiology

  • epitope — The simplest form of an antigenic determinant, on a complex antigenic molecule, which can combine with antibody or T cell receptor. [epi + tope] shared e. SYN: susceptibility cassette. * * * e …   Medical dictionary

  • epitope — ep•i•tope [[t]ˈɛp ɪˌtoʊp[/t]] n. imu a site on an antigen at which an antibody can bind, the molecular arrangement of the site determining the specific combining antibody Also called antigenic determinant • Etymology: 1970–75; epi + tope < Gk… …   From formal English to slang

  • Linear epitope — A linear or a sequential epitope is an epitope that is recognized by antibodies by its linear sequence of amino acids, or primary structure. In contrast, most antibodies recognize a conformational epitope that has a specific three dimensional… …   Wikipedia

  • Conformational epitope — Recognition of conformational epitopes by B cells. Note how the segments widely separated in the primary structure have come in contact in the three dimensional tertiary structure forming part of the same epitope[1] A conformational epitope is a… …   Wikipedia

  • Mimotop — Mimotope (von engl. mimic, nachahmen und Epitop) sind künstlich hergestellte Peptide oder kleine Proteine, welche die strukturellen Erkennungsmerkmale eines Antigens, die sogenannten Epitope, nachahmen. Mimotope werden wie ihre Vorbilder von… …   Deutsch Wikipedia

  • PTPRN — Protein tyrosine phosphatase, receptor type, N, also known as PTPRN, is a human gene.cite web | title = Entrez Gene: PTPRN protein tyrosine phosphatase, receptor type, N| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Molecular mimicry — is defined as the theoretical possibility that sequence similarities between foreign and self peptides are sufficient to result in the cross activation of autoreactive T or B cells by pathogen derived peptides. Despite the promiscuity of several… …   Wikipedia

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia


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